Tuesday, January 31, 2012

Syria says 'terrorists' blow up gas pipeline (AP)

BEIRUT ? An "armed terrorist group" in Syria blew up a gas pipeline at dawn Monday, the state-run media said, as activists reported gunfire and explosions in the suburbs of Damascus as the country's conflict moves ever closer to the capital.

The pipleline carries gas from the central province of Homs to an area near the border with Lebanon. SANA news agency reported that the blast happened in Tal Hosh, which is about five miles (eight kilometers) from Talkalakh, along the border with Lebanon.

Further details were not immediately released.

There have been several pipeline attacks since the Syrian uprising began in mid-March, but it is not clear who is behind them.

President Bashar Assad's regime has blamed "terrorists" for driving the country's 10-month-old uprising, not protesters seeking democratic change.

On Sunday, Syrian troops in dozens of tanks and armored vehicles stormed rebellious areas near the capital, shelling neighborhoods that have fallen under the control of army dissidents and clashing with fighters.

Activists and residents said at least 62 people were killed in violence nationwide.

The large-scale Sunday offensive suggested the regime is worried that military defectors could close in on Damascus, the seat of Assad's power. Early Monday, activists reported hearing gunfire and blasts in the Damascus suburbs, but there were no details.

The rising bloodshed added urgency to Arab and Western diplomatic efforts to end the 10-month conflict.

In the past two weeks, army dissidents have become more visible near the capital, seizing several suburbs on the eastern edge of Damascus and setting up checkpoints where masked men wearing military attire and wielding assault rifles stop motorists and protect anti-regime protests.

Their presence so close to the capital is astonishing in tightly controlled Syria and suggests the Assad regime may either be losing control or setting up a trap for the fighters before going on the offensive.

The uprising against Assad, which began with largely peaceful demonstrations, has grown increasingly militarized recently as more frustrated protesters and army defectors have taken up arms.

In a bid to stamp out resistance in the capital's outskirts, the military has responded with a withering assault on a string of suburbs, leading to a spike in violence that has killed at least 150 people since Thursday.

The United Nations says at least 5,400 people have been killed in the 10 months of violence.

The U.N. is holding talks on a new resolution on Syria and next week will discuss an Arab League peace plan aimed at ending the crisis. But the initiatives face two major obstacles: Damascus' rejection of the Arab plan that it says impinges on its sovereignty, and Russia's willingness to use its U.N. Security Council veto to protect Syria from sanctions.

Source: http://us.rd.yahoo.com/dailynews/rss/world/*http%3A//news.yahoo.com/s/ap/20120130/ap_on_re_mi_ea/ml_syria

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Monday, January 30, 2012

Don't blame C-sections for fat children: study (Reuters)

(Reuters) ? Children born by Cesarean section are no more likely to become obese than if they are born vaginally, according to a Brazilian study.

Past research from Brazil had found a link between excessive weight and C-sections, leading some scientists to suggest that not being exposed to bacteria from the birth canal could make children fatter, but the latest findings -- published in the American Journal of Clinical Nutrition -- suggest this doesn't appear to be the case.

The research is of particular interest in Brazil, because in 2009 more than half of the babies there were born by C-section. In the United States, the number has been on the rise for years and is now over 30 percent.

"We thought from the beginning that probably what happened with the previous study is that they didn't adjust for all of the confounders," said Fernando Barros of the Catholic University of Pelotas, who worked on the study, referring to factors such as the mother's height and weight.

Barros and his colleagues used data on three groups of several thousand people born in Southern Brazil in 1982, 1993 or 2004.

Researchers contacted the children at different ages until the oldest had turned 23. Those born by C-section were more likely to be heavy, with obesity rates between nine and 16 percent, compared to rates of seven to 10 percent of children born vaginally.

However, that difference vanished once the researchers accounted for factors such as family income, birth weight, schooling and the mother's weight, height, age and smoking habits.

"When you factor in all of these other factors, the relationship between obesity and Cesarean sections disappears," said Barros.

The earlier Brazilian study left out many of those factors, including maternal height and weight, Barros's team wrote in its report.

"The really simple explanation would be that more obese women require more Cesarean sections than lean women... and it's really not the C-section itself," said David Ludwig, director of the Optimal Weight for Life Clinic at Children's Hospital, Boston, who was not involved in the study.

He said that things such as a pregnant woman's diet and smoking habits, and whether or not she has diabetes, might influence a developing fetus.

Some believe that C-section babies are different because they are not exposed to bacteria in the birth canal like babies born vaginally. The theory is part of a hypothesis which suggests that a person's immune system develops differently when they're not exposed to beneficial bacteria early in life.

"We're not saying this hypothesis is not interesting. It is. We're just saying, right now, without data, we cannot confirm the finding," Barros said. SOURCE: http://bit.ly/zjs00B

(Reporting from New York by Andrew Seaman; editing by Elaine Lies)

Source: http://us.rd.yahoo.com/dailynews/rss/parenting/*http%3A//news.yahoo.com/s/nm/20120130/hl_nm/us_c_section

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The Rise of Private Health Insurance Plans

Best Type of Health Insurance - For You

Should You Choose an HSA, HMO, or PPO Health Insurance Plan?

Preferred Provider Organization (PPO): These are similar to HMO plans. They also have a network of medical providers.

Many people like PPO plans because they are more flexible than HMO plans.

HSA Health Plans (Health Savings Accounts): These are a little different. You will get a high deductible major medical insurance plan with a health savings account.

  • Many accounts pay interest at competitive rates.

?

Medicare supplement plans are not issued by private insurance companies to compete with the Federal Government?s Medicare. Instead, Medicare and Medicare supplement plans would work hand-in-hand in answering the growing health care needs of Americans. Medicare is the prime source of insurance coverage while Medicare supplement plans covering parts of the expenses.

will remain supplemental.; There are still some aspects of health care coverage that private health insurance plans cannot cover. Despite that, however, Medicare supplement plans still offer the practical approach to Americans who are concerned about health care: a mix of Medicare and Medicare supplement plans to answer health care and medical insurance needs.

Source: http://www.umdelts.org/the-rise-of-private-health-insurance-plans

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Russian great Plushenko wins 7th European title

Russia's Evgeni Plushenko celebrates after performing in the Men's Free Skating program competition at the European Figure Skating Championships in Sheffield, England, Saturday Jan. 28, 2012. (AP Photo/Jon Super)

Russia's Evgeni Plushenko celebrates after performing in the Men's Free Skating program competition at the European Figure Skating Championships in Sheffield, England, Saturday Jan. 28, 2012. (AP Photo/Jon Super)

Russia's Evgeni Plushenko kisses his gold medal after winning the Men's Free Skating event at the European Figure Skating Championships in Sheffield, England, Saturday Jan. 28, 2012. (AP Photo/Jon Super)

Russia's Evgeni Plushenko kisses his gold medal after winning the Men's Free Skating event at the European Figure Skating Championships in Sheffield, England, Saturday Jan. 28, 2012. (AP Photo/Jon Super)

France's Florent Amodio celebrates after winning bronze medal in the Men's Free Skating event at the European Figure Skating Championships in Sheffield, England, Saturday Jan. 28, 2012. (AP Photo/Jon Super)

(AP) ? Russian great Evgeni Plushenko produced a career-best performance Saturday to beat protege Artur Gachinski and win his seventh men's European figure skating title.

The 2006 Olympic champion put together a compelling routine to "Tango de Roxanne" from the Moulin Rouge soundtrack and scored a personal-best 176.52 points in the free skate for a total of 261.23 ? Plushenko's highest ever overall mark.

His breathtaking display included a perfectly judged quadruple jump ? an exploit he claimed he couldn't perform this week because of injuries to his left knee and back.

"I did a little bit of history in figure skating today," an overjoyed Plushenko said.

The 18-year-old Gachinski led his mentor, idol and training partner by 0.09 points after the short program but finished 14.96 points behind in second with 246.27. Gachinski, the bronze medalist from last year's worlds, scored 161.47 points in his free skate for a 246.27 total.

Defending champion Florent Amodio of France rallied from fifth place to take the bronze with an overall score of 234.18, ahead of Michal Brezina of the Czech Republic (153.17).

With the spectators at Motorpoint Arena already rising to their feet, Plushenko ? dressed in a glitter-lined black outfit ? put an exclamation point on his routine with repeated fist pumps at the end.

Even with Gachinski and three other rivals to come, the greatest male skater of his generation knew the gold was again his at age 29 ? 12 years after winning his first continental title.

"You all saw my emotions at the end," Plushenko said. "I felt like I did eight years ago."

Plushenko is a sporting icon in Russia, and the only living male skater with three Olympic medals to his name. Having started his senior career in 1997, he will attempt to stay on until the 2014 Olympics on home soil in Sochi.

"When I am going to be healthy, I will do a little bit more," said Plushenko, who will head to Germany to undergo surgery on his problematic left knee in two weeks ? a procedure that will keep him out of the world championships at the end of March.

His previous best overall score was 258.33 when he won gold at the 2006 Turin Games. He scored 167.67 in the free skate in that competition, his previous best mark for the longer of the two disciplines.

Plushenko's excuse for not doing a quad during his play-it-safe short program on Thursday was that it would take 3 or 4 minutes for his body to recover.

Lo and behold, Plushenko opened the free skate with a quad toe loop ? which earned the maestro 11.59 points ? and set the tone for the rest of a joyous and nearly flawless routine that had the crowd transfixed.

The veteran skater denied he had played mind games with his rivals, insisting instead that his medical team had performed miracles.

"Today, the problems with my meniscus were overcome," he said. "Today, I skated at full capacity."

He went on to nail both a triple axel-triple toe and then a triple lutz-double toe-double loop combination, and achieved a level four with his flying sit spin and camel spin.

The intimidating score left him way clear of the field. Gachinski, Javier Fernandez and Amodio had yet to skate, but following Plushenko was virtually impossible.

Needing to skate the best routine of his young career, Gachinski opened up stylishly with a quad toe combination and another quad toe but was marked down on his latter jumps.

"I am still happy," said Gachinski, who also broke his personal best of 241.86 points. "This is my second Europeans and I got a second."

Tomas Verner of the Czech Republic was third after the short program but flopped in the free, slumping to fifth and allowing Amodio to climb onto the podium despite the Frenchman not managing a quad.

"It was a difficult experience but I'm proud," Amodio said. "I started to feel like the real Florent Amodio."

The women's title will be decided later Saturday, with Italy's Carolina Kostner in the lead after the short program as she goes in search of a fourth European gold.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/347875155d53465d95cec892aeb06419/Article_2012-01-28-FIG-European-Championship/id-3fd9187623424927a2969557266e1a5a

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Sunday, January 29, 2012

Rubinstein, who revitalized Palm, leaves HP

The future is mobile, says the former Apple executive, who had seen his role reduced after Hewlett-Packard killed off his webOS for the handheld Palm. Rubinstein is taking a break.?

Jon Rubinstein, the former Apple executive who spearheaded engineering for the iPod, and then proceeded to revitalize Palm, has officially left Hewlett-Packard, the company confirmed today.

Skip to next paragraph

The news isn?t entirely unexpected. Rubinstein was reportedly a no-show at HP since former CEO Leo Apotheker?killed off the company?s WebOS devices. Even before that his role at HP was reduced with a change to a vague ?SVP of innovation? title.

An HP spokesperson?told All Things Digital, which first reported the news about Rubinstein?s departure, that ?Jon has fulfilled his commitment and we wish him well.? Rubinstein confirmed that he only agreed to stick around HP for 12 to 24 months after it acquired Palm, in?an interview with The Verge.

Speaking to the Verge?s Joshua Topolsky, Rubinstein deftly avoided chatting about where Palm went wrong or complaining about Apotheker?s treatment of webOS:

We built an amazing OS in webOS. It?s very advanced, it?s where things are going. But we ran out of runway, and we ended up at HP and HP wasn?t in good enough shape on its own to be able to support the effort. I had four CEOs! Mark acquired us, Les Jackson took over as the interim CEO, then Leo, and now Meg.

Now Rubinstein, seemingly going full circle, is taking a much-deserved break in Mexico, where the Palm folks initially tapped him to help save the company in 2007. He admitted that he?s still carrying a tiny webOS-powered Veer, and that he hopes to get back into the mobile world in some fashion.

?I think the future is mobile,? Rubinstein told the Verge. ?Obviously there?s going to be stuff that comes post mobile, there?ll be a next wave. It could very well be home integration, but mobile?s going to continue to be really important. But I have no idea what I?m going to do next. I haven?t spent a minute thinking about it.?

See also:

Jack Dorsey, Ron Conway to attend The Crunchies?Awards?
Silicon Valley and Colorado companies ? Do you sizzle??(Reminder)

Source: http://rss.csmonitor.com/~r/feeds/csm/~3/6d_lsLoPFiA/Rubinstein-who-revitalized-Palm-leaves-HP

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France to cut Afghan combat role, leave 2013 (Reuters)

PARIS (Reuters) ? French troops will start handing over security to the Afghan army in March and focus on training until pulling out of Afghanistan completely at the end of 2013, President Nicolas Sarkozy said on Friday.

Sarkozy suspended training and support operations on the ground last week and sent his defense minister and armed forces chief to Kabul after four of their soldiers were killed by a rogue Afghan soldier.

While the French decision was not an outright retreat, the move effectively brings an end to Paris' frontline military operations, a decision that could prove a boost to Sarkozy ahead of a presidential election.

Paris has 3,600 troops in Afghanistan as part of the 130,000-strong NATO-led force. French troops mainly patrol Kapisa, a mountainous province near Kabul.

Speaking after talks with Afghanistan President Hamid Karzai in Paris, Sarkozy said France would only have a training-and-support role once Kapisa is handed over.

"President Karzai has assured us that Kapisa province where the French contingent is based will pass under Afghan responsibility from March," Sarkozy said.

One thousand French troops were due to leave by the end of 2012 and the rest by 2014.

"From that point on France will engage in training and support activities," Karzai said.

"It is right that Afghanistan has to provide for its own security and protection of its own people and provision of law and order. Afghanistan is now ready to take more of this responsibility."

In Washington, the State Department gave a measured response to Sarkozy's decision, which it said had been thoroughly discussed both with NATO and with the Afghan government.

"What we are gratified by is that this was not precipitous, that this was worked through carefully with NATO, with the Afghans and in consultation with all of us," State Department spokeswoman Victoria Nuland told reporters.

"This was a national decision of France. It was done in a managed way. We will all work with it," Nuland said, referring any questions on the operational impact of the French pullout.

Sarkozy said he would speak with U.S. President Barack Obama on Saturday and Paris was preparing a plan to present to NATO at a defense ministers meeting on February 2-3 proposing the handover of all foreign combat operations in Afghanistan next year.

"It's important that you understand that this agreement was done with President Karzai and with our allies in an organized and reasonable manner," Sarkozy said. "Our soldiers have done a tremendous job in Kapisa. We are not an occupying force."

ELECTION BOOST

Sarkozy said French troops would resume training operations tomorrow after receiving security guarantees from Karzai and the two leaders would also ask NATO to look deeper into the problem of Taliban infiltrators in the Afghan army and police.

Sarkozy's Socialist rival Francois Hollande, who is comfortably ahead in the polls, has pledged to pull out of Afghanistan by the end of this year if he wins the election held in two rounds in April and May.

In a CSA survey published on Thursday, 84 percent of people said they were in favor of troops leaving by the end of 2012.

Foreign Minister Alain Juppe has ruled out a "hasty" retreat and most analysts believe it will technically be difficult for Paris to drop out of the NATO-led coalition so quickly.

"Announcing a French withdrawal could set off panic among other European countries in Afghanistan," said military analyst Jean-Dominique Merchet.

The killings in the Taghab valley of Afghanistan's eastern Kapisa province were the latest in a series of incidents in which Afghan troops have turned on Western allies.

More than 2,500 foreign soldiers have died in Afghanistan since 2001. The latest killings take the French toll to 82.

NATO has been rapidly expanding the Afghan security forces so that they will be able to take over all responsibility for security when Western combat forces leave in 2014.

Kabul and Paris also signed a cooperation treaty for post- 2014. The agreement will see several hundred French military advisers stay to continue training Afghan soldiers and police. It will also set out several scientific, cultural, technical and infrastructure accords for various sectors ranging over agriculture, health and transport.

(Reporting By John Irish)

Source: http://us.rd.yahoo.com/dailynews/rss/asia/*http%3A//news.yahoo.com/s/nm/20120127/wl_nm/us_france_afghanistan

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Saturday, January 28, 2012

Oil near $100 as Fed vows to keep key rate low (AP)

BANGKOK ? Oil rose to near $100 a barrel Thursday in Asia after the U.S. Federal Reserve said it would keep interest rates at record lows at least until 2014 to help jump-start the world's biggest economy.

Benchmark crude for March delivery was up 43 cents at $99.83 a barrel at late afternoon Bangkok time in electronic trading on the New York Mercantile Exchange. The contract rose by 45 cents to finish at $99.40 per barrel in New York on Wednesday. At one point it was as high as $100.40.

Brent crude for March delivery was up 71 cents at $110.52 a barrel on the ICE Futures Exchange in London.

The U.S. central bank, which has kept its benchmark interest rate near zero for three years, said Wednesday that it doesn't plan to raise the rate before late 2014.

That caused the dollar to turn lower against major currencies, which makes dollar-priced oil less expensive for holders of other currencies.

"That would mean the U.S. dollar would continue to be cheap versus other currencies, and there is typically an inverse correlation between the value of the dollar and commodity pricing," said Victor Shum, an energy analyst at consultancy Purvin & Gertz in Singapore.

"So oil prices are supported by the Federal Reserve statement," he said.

But other analysts saw room for oil prices to fall.

Leaving rates low would encourage businesses and consumers to borrow money cheaply, boosting the economy and leading to higher oil demand. But the Fed also "telegraphed its concern regarding U.S. economic growth ... which is intuitively bearish for oil," said energy trader and consultant The Schork Group.

In other Nymex trading, heating oil rose 2.3 cents to $3.03 per gallon and gasoline futures gained 1 cent to $2.85 per gallon. Natural gas advanced 3.9 cents to $2.77 per 1,000 cubic feet.

Source: http://us.rd.yahoo.com/dailynews/rss/energy/*http%3A//news.yahoo.com/s/ap/20120126/ap_on_bi_ge/oil_prices

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Friday, January 27, 2012

Survival rates for pediatric bone marrow transplants top in nation

Survival rates for pediatric bone marrow transplants top in nation [ Back to EurekAlert! ] Public release date: 26-Jan-2012
[ | E-mail | Share Share ]

Contact: Juliana Bunim
juliana.bunim@ucsf.edu
415-502-6397
University of California - San Francisco

UCSF also rates as 'over performer' for adult survival rates

The UCSF Benioff Children's Hospital has the best overall survival rates in the nation for bone marrow transplants, according to a recent independent review of 156 programs nationwide.

The Pediatric Blood and Marrow Transplant Program, led by Morton Cowan, MD, was ranked number one for survival performance by the federally mandated review program of the Center for International Blood and Marrow Transplant Research (CIBMTR).

The 156 transplant centers were reviewed based on the number of transplants done annually, adjusted for risk, and estimated the chance for survival one year post transplant. Overall, the estimated chance of survival after one year was 63.4 percent. Of the 156 centers reviewed, only 14 (9 percent) were considered over performers, with the UCSF Pediatric Bone Marrow Transplant Program ranked number one with a survival rate of 87.6 percent.

Additionally, the Adult Hematology and Blood and Marrow Transplant (BMT) at UCSF Medical Center was again named an "over performer" by the CIBMTR. This is the second consecutive year the service has been recognized as an over performer. The adult program is also one of 14 nationwide recognized for exceeding U.S. expectations in patient survival rates for those undergoing a blood or marrow transplant from either a relative or an unrelated donor. At UCSF, 75 percent of adult patients receiving a BMT survive at least a year, compared to the national average of 63.4 percent.

Christopher Dvorak, MD, a pediatric blood and bone marrow transplant specialist at the UCSF Benioff Children's Hospital, wasn't surprised by the results knowing firsthand the level of commitment to success that exists within and well beyond the pediatric BMT team.

"We work incredibly hard and have an attention to detail and dedication to our policies attempting to limit transplant-associated mortality," said Dvorak, who is also head of the national Pediatric Blood and Marrow Transplant Consortium's Supportive Care Strategy Sroup.

The UCSF pediatric BMT program has expanded in recent years by adding two physicians and two nurse practitioners, ultimately increasing the number of transplants performed. UCSF's interdisciplinary collaboration among health care professionals also adds a nuanced level of support. "Some of the credit for our success must go to the pediatric intensive care unit which helps patients survive when then get critically ill," Dvorak said.

The pediatric BMT unit also gives more individualized attention to the dosing of chemotherapy medications through increased interactions with the UCSF School of Pharmacy. "We have a great School of Pharmacy and now have a doctor of pharmacy on our team, helping us with tailoring the chemo regimens. We have great nurses and nurse practitioners through the School of Nursing as well, and all of that plays into our success."

While adult bone marrow transplants are usually performed to treat blood-related cancers, pediatric transplants are necessary for a host of other reasons. Immunodeficiency syndromes, defects in red blood cells, inborn errors of metabolism, and several types of cancer account for many of the BMT transplants performed in children at UCSF.

###

Since the UCSF Pediatric Bone Marrow Transplant Program was started by Cowan in 1982, nearly 1,000 transplants have been performed at UCSF Benioff Children's Hospital. In 1982, UCSF performed the first partially matched bone marrow transplant on the West Coast, using bone marrow from a parent for a child with a severe immunodeficiency disease.

Today, UCSF is a leader in special treatment options for children with primary immunodeficiency diseases, marrow failure syndromes, genetic diseases, cancers and other life-threatening illnesses.

UCSF is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care.

Follow UCSF http://www.UCSF.edu | http://www.Facebook.com/ucsf | http://www.Twitter.com/ucsf | http://www.YouTube.com/ucsf



[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Survival rates for pediatric bone marrow transplants top in nation [ Back to EurekAlert! ] Public release date: 26-Jan-2012
[ | E-mail | Share Share ]

Contact: Juliana Bunim
juliana.bunim@ucsf.edu
415-502-6397
University of California - San Francisco

UCSF also rates as 'over performer' for adult survival rates

The UCSF Benioff Children's Hospital has the best overall survival rates in the nation for bone marrow transplants, according to a recent independent review of 156 programs nationwide.

The Pediatric Blood and Marrow Transplant Program, led by Morton Cowan, MD, was ranked number one for survival performance by the federally mandated review program of the Center for International Blood and Marrow Transplant Research (CIBMTR).

The 156 transplant centers were reviewed based on the number of transplants done annually, adjusted for risk, and estimated the chance for survival one year post transplant. Overall, the estimated chance of survival after one year was 63.4 percent. Of the 156 centers reviewed, only 14 (9 percent) were considered over performers, with the UCSF Pediatric Bone Marrow Transplant Program ranked number one with a survival rate of 87.6 percent.

Additionally, the Adult Hematology and Blood and Marrow Transplant (BMT) at UCSF Medical Center was again named an "over performer" by the CIBMTR. This is the second consecutive year the service has been recognized as an over performer. The adult program is also one of 14 nationwide recognized for exceeding U.S. expectations in patient survival rates for those undergoing a blood or marrow transplant from either a relative or an unrelated donor. At UCSF, 75 percent of adult patients receiving a BMT survive at least a year, compared to the national average of 63.4 percent.

Christopher Dvorak, MD, a pediatric blood and bone marrow transplant specialist at the UCSF Benioff Children's Hospital, wasn't surprised by the results knowing firsthand the level of commitment to success that exists within and well beyond the pediatric BMT team.

"We work incredibly hard and have an attention to detail and dedication to our policies attempting to limit transplant-associated mortality," said Dvorak, who is also head of the national Pediatric Blood and Marrow Transplant Consortium's Supportive Care Strategy Sroup.

The UCSF pediatric BMT program has expanded in recent years by adding two physicians and two nurse practitioners, ultimately increasing the number of transplants performed. UCSF's interdisciplinary collaboration among health care professionals also adds a nuanced level of support. "Some of the credit for our success must go to the pediatric intensive care unit which helps patients survive when then get critically ill," Dvorak said.

The pediatric BMT unit also gives more individualized attention to the dosing of chemotherapy medications through increased interactions with the UCSF School of Pharmacy. "We have a great School of Pharmacy and now have a doctor of pharmacy on our team, helping us with tailoring the chemo regimens. We have great nurses and nurse practitioners through the School of Nursing as well, and all of that plays into our success."

While adult bone marrow transplants are usually performed to treat blood-related cancers, pediatric transplants are necessary for a host of other reasons. Immunodeficiency syndromes, defects in red blood cells, inborn errors of metabolism, and several types of cancer account for many of the BMT transplants performed in children at UCSF.

###

Since the UCSF Pediatric Bone Marrow Transplant Program was started by Cowan in 1982, nearly 1,000 transplants have been performed at UCSF Benioff Children's Hospital. In 1982, UCSF performed the first partially matched bone marrow transplant on the West Coast, using bone marrow from a parent for a child with a severe immunodeficiency disease.

Today, UCSF is a leader in special treatment options for children with primary immunodeficiency diseases, marrow failure syndromes, genetic diseases, cancers and other life-threatening illnesses.

UCSF is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care.

Follow UCSF http://www.UCSF.edu | http://www.Facebook.com/ucsf | http://www.Twitter.com/ucsf | http://www.YouTube.com/ucsf



[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2012-01/uoc--urf012612.php

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Thursday, January 26, 2012

Foreclosures made up 20 pct. of home sales in 3Q

(AP) ? Foreclosures made up a smaller slice of all U.S. homes sold in last year's third quarter, as banks delayed placing properties for sale and home sales slowed.

Despite the decline, foreclosures still represented 20 percent of all homes sold in the July-September period ? about four times more than at the height of the housing boom, foreclosure listing firm RealtyTrac Inc. said Thursday.

Foreclosure sales include homes purchased after they received a notice of default or were repossessed by lenders.

In 2005 and 2006, when housing was still flying high, foreclosures made up less than 5 percent of all home sales, the firm said. They peaked in 2009 at 37.4 percent.

As a portion of all homes purchased, foreclosure sales declined in the third quarter from 22 percent in the April-June period. They were down from 30 percent in the third quarter of 2010, RealtyTrac said.

Sales of all previously occupied homes rose in August, but fell in July and September, according to the National Association of Realtors. Sales of new homes, which account for less than 10 percent of the housing market, fell in July and August, but rose in September.

Ongoing disputes over how some lenders handled foreclosures have been a key factor in foreclosed homes' declining share of all home sales.

In the fall of 2010, some banks and mortgage servicers were found to have been signing off on home foreclosures without first verifying documents, a practice dubbed "robo-signing." That sparked a state and federal probe and prompted many lenders to revisit their foreclosure procedures. Many also delayed taking action against homeowners behind on their mortgage payments.

The delays coupled with uncertainty over the outcome of negotiations to settle the banking-industry probe have led to fewer foreclosed homes being put up for sale.

But housing industry experts say they anticipate that will change swiftly once the investigations are resolved. They note the glut of bank-owned homes and others already in some stage of foreclosure.

"As the foreclosure industry gets clarity on the foreclosure process, they will be able to push more of these foreclosures to sale," said Daren Blomquist, a vice president at RealtyTrac.

As of Dec. 31, there were more than 680,000 U.S. homes owned by banks and another 715,000 in some stage of foreclosure, Blomquist said.

All told, 221,536 bank-owned homes and others in the foreclosure process were sold in 2011's third quarter. That's down 11 percent from the second quarter and down 5 percent from the third quarter of 2010.

Foreclosures, often in need of repair, typically sell at big discounts and weaken prices for neighboring homes.

Homebuyers who purchased a foreclosure in the third quarter paid an average of $165,322, representing a discount of 34 percent from the average sale price of all other homes, RealtyTrac said.

The discount was unchanged from the April-June quarter, but declined from 37 percent in the third quarter of 2010.

Bank-owned homes, which are sold after being repossessed, accounted for nearly 12 percent of all sales in the third quarter. Sales of homes in the foreclosure process ? properties in default or scheduled for auction ? made up about 9 percent of all sales.

Nevada led all states with foreclosure sales accounting for nearly 57 percent of all home sales, RealtyTrac said.

Several other states had foreclosure sales that made up at least 20 percent of all homes purchased in the third quarter: California, Arizona, Georgia, Colorado and Michigan.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/f70471f764144b2fab526d39972d37b3/Article_2012-01-26-Foreclosure%20Sales/id-54f8ca59dba74a0ab37157c42950a2fc

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Libyan government concedes to restive town's demands (Reuters)

TRIPOLI (Reuters) ? Libya recognized a tribal-based local government in the former Gaddafi stronghold of Bani Walid on Wednesday, illustrating the power of tribal leaders over the fragile interim government.

Fighters from the Warfallah tribe -- the dominant tribe in Bani Walid and the most populous in Libya -- drove out a pro-government militia from the town this week.

Salah al-Maayuf, a member of the Warfallah Elders Council in Bani Walid, said his tribal body appointed a new local council on Tuesday and that Defense Minister Osama al-Juwali recognized the body during all-day talks on Wednesday.

"The Defense minister told us that if we, as a tribe, believe that the new local council in Bani Walid will work, then we have convinced him that it can," Maayuf told Reuters from Bani Walid, a bastion of support for former leader Muammar Gaddafi during last year's rebellion.

"We told him that we want to keep the whole country peaceful

and that national unity was a priority," Maayuf added.

An official at the Defense ministry confirmed that Juwali had accepted the new council, but did not give further details.

NTC RETREATS

Juwali is a member of the provisional government installed in November by the National Transitional Council (NTC), the self-appointed body which won Western backing in the uprising that ousted Gaddafi in August.

On Monday, armed residents attacked the barracks of the NTC force in the town, killing four fighters by the account of the government militia, and forcing the unit to retreat to beyond the desert city's limits. Eight of the town's residents were also killed, doctors at the hospital said.

Echoing complaints by residents that the NTC fighters had been harassing people, making arrests and abusing prisoners, the town's elders said on Tuesday they did not want any interference from the Tripoli authorities and dismissed the local NTC council.

The unrest will heighten doubts about the NTC's ability to bring order and establish control over armed groups - goals crucial to rebuilding oil exports and securing Libya's vast desert borders in a region where al Qaeda is active.

Bani Walid, in Libya's Western Mountains 150 km (90 miles) south of Tripoli, was one of the last towns to surrender to the anti-Gaddafi rebellion last year. But residents reject accusations from NTC fighters that they remain loyal to Gaddafi.

After Gaddafi was captured and killed in October, one of his sons, the now captive Saif al-Islam, staged his last stand in Bani Walid before fleeing into the Sahara.

Reuters reporters who toured Bani Walid on Tuesday saw no signs of the Gaddafi-era green flags which NTC supporters said had been hoisted over the town following the retreat of the pro-government militia.

Some pro-Gaddafi graffiti remains in the town, but the most common banners flying were the red, green and black tricolor of the NTC.

GOVERNMENT FORCES SURROUND THE TOWN

Bani Walid is not alone. Towns and cities across Libya are being run with little reference to central authority. In a number of areas tensions have emerged between groups which were nominally allies in the revolt.

Abdul Azziz al-Jmaili, a resident of Bani Walid, said government forces were around the town to prevent escalating fighting.

Speaking to Reuters by telephone, Jmaili said a "peacekeeping force" comprised of units of former rebel fighters loyal to the NTC and drawn from other towns in the region had set up checkpoints in the outskirts of Bani Walid.

(Additional reporting by Taha Zargoun and Oliver Holmes; Writing by Oliver Holmes; Editing by Rosalind Russell)

Source: http://us.rd.yahoo.com/dailynews/rss/africa/*http%3A//news.yahoo.com/s/nm/20120125/wl_nm/us_libya_talks

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Tuesday, January 24, 2012

A year on, has Egypt's revolution stalled? (Reuters)

CAIRO (Reuters) ? A few dozen activists huddle around tents on a grubby traffic island in Cairo's Tahrir Square, a forlorn reminder of the revolutionary ardor that ended Hosni Mubarak's 30-year rule.

A year on, the revolution that youth activists spearheaded appears to have stalled as the military rulers who replaced Mubarak seem to be exploiting opposition splits and popular fears of chaos to shore up their power and limit the scope of change.

Many Egyptians admire the youthful fervor of the revolutionaries but oppose their implacable hostility to the military caretakers, who have pledged to step aside by mid-year and hand power to elected civilians.

In a nod of approval to the army's transition timetable, voters have thronged polls for Egypt's first free parliamentary vote in decades and elected an assembly dominated by Islamists.

Their victory is a huge change in itself. Egyptians speak more freely a year on, their daily protests evidence both of newfound liberties and hope that people can make a difference.

For activists, however, the revolution will be incomplete as long as the army remains in power. Too little has changed, they say, to end a street movement demanding deeper, broader, faster reform. New campaigns have been born, such as 3askar Kaziboon, or Military Liars, in which activists roam the streets showing videos of protesters wounded since the end of the 18-day revolt.

"The more time has passed the more people have become convinced that the regime has not changed... They decapitated the regime so that the people would calm down, convinced that change has happened when it has not," said Amal Bakry of the No To Military Trials pressure group set up after the revolt. "It's still present in its ministers, its government, in everything."

Kamal al-Ganzouri, the generals' choice for prime minister, led the cabinet under Mubarak in the 1990s.

Mohamed Hussein Tantawi, the general who is now Egypt's ruler, was Mubarak's defense minister for two decades. A leaked U.S. embassy cable said officers called him Mubarak's "poodle."

An emergency law in force since 1981 remains. The generals say it is necessary to keep order, but activists say it allows them to ride roughshod over civil liberties as Mubarak once did.

No To Military Trials estimates 12,000 people have been referred to military courts since Mubarak fell, four times the number who faced that fate during his 30-year tenure, when state security courts were the venue of choice for emergency trials.

Some were jailed for their criticism of the military council and now speak of a campaign to crush the pro-democracy movement.

Sipping tea at a cafe in an upscale district of Cairo, Bakry said her group struggled, at first, to convince Egyptians that the army was trying to block real democratic change.

The army was feted for pushing Mubarak aside last February and ensuring order when his hated state security forces fled the streets, but its handling of street protests in recent months has appeared at times to take a leaf out of Mubarak's book.

In October, at least 25 people were killed near the state media building in Cairo. Protesters say military police drove vehicles into a crowd of protesters and fired live shots. The army blamed foreign elements and other instigators. Watching state media, some Egyptians thought the army had been attacked.

"People were not emotionally ready to face the truth," Bakry said. "They did not want to admit that the revolution had been defeated and ... that the army, so highly regarded among the people, was doing all these things."

TRANSITION TO CIVILIAN RULE

Egyptians willing to give the army the benefit of the doubt went out to vote for parliament from November 28 and found they could cast their ballots for the first time without fear of intimidation from thugs or finding ballot boxes already stuffed.

The new assembly, which held its first sitting on Monday, is dominated by the Muslim Brotherhood -- officially banned from politics under Mubarak.

Egyptians speak more freely since the revolt, they can and do protest more freely despite repeated crackdowns and they have set up a dizzying number of political parties in recent months.

There has been an increase in what activist Mozn Hassan, head of Nazra for Feminist Studies, calls "active citizenship."

"It could fail, it could be stolen but there are spaces and subjects open now that you could not discuss in 2010," she said.

"Whether you like what happened or not, there has been an experience with political parties now."

But critics question how much say new deputies will have in drafting the new constitution or naming the government. Under the latest timetable, there will be a two-month window from the end of parliamentary elections in March to presidential polls in June in which to name a 100-member body to draft the document, agree on its contents and put it to a referendum.

To those who have campaigned for years for an empowered parliament and for the rule of law, it seems the generals are railroading the reform process. The army says it will not field a presidential candidate, but activists worry it will back its preferred choice via state media, with others unable to compete.

Veteran activist and politician Ayman Nour told Reuters the army was conceding control of parliament to politicians while trying to keep its grip over the powerful presidency.

"They see it as them giving parliament to political forces, or Islamic forces, while they keep their right to a president who belongs to them," he said. "They want a person to whom they can give instructions, who guarantees loyalty to them."

Disappointed by what they see as the superficial reforms of the army-led transition, candidates have quit the presidential race. Mohammed ElBaradei, former head of the U.N. nuclear agency, withdrew complaining too little had changed. So has Nour, the only man to ever challenge Mubarak to the presidency.

Since the uprising, Nour has failed to overturn a Mubarak-era conviction on charges of falsifying party registration documents that bars him from the presidential race. Critics complain that Egypt's judiciary is still filled with Mubarak-era appointees who resist change. Mubarak-era laws remain in place.

"I warned from Tahrir Square of the danger of leaving responsibility in the hands of the army, and I said clearly that I fear the military beret and the religious turban," Nour said.

"The counter-revolution is managing Egypt now."

ONE YEAR ON

Egypt's most powerful Islamist force, the Muslim Brotherhood, has largely kept its followers off the streets to focus on winning elections, consolidating its power inside parliament and working through the institutions of state.

Egyptians tired of political turbulence that has hit the economy and keen to restore normality, say it is time to end protests and give the newly-elected parliament a chance.

Despondent at the Brotherhood's position, street activists want to wrest back the initiative and are urging mass protests against the generals on the January 25 anniversary of the uprising.

With marches, wall art and videos of wounded protesters, activists are trying to revive the euphoria that swept the Arab world in 2011 for fear that creeping fatalism among their compatriots could allow Egypt to return to authoritarian rule.

"I am against protesting on January 25. Military rule will be meaningless after the parliamentary and presidential election; you are rushing something that if you wait will come on its own," said 30-year-old Ahmed Farouq, an optician who, like some two thirds of Egyptians, voted for Islamists. "Ordinary citizens want to calm down and achieve stability."

The army has declared January 25 a public holiday to celebrate, part of what critics say is an effort to appropriate what the revolution stands for and limit calls for change. It appears to have stepped up Mubarak-era scrutiny of civil society groups.

In December, Egyptian authorities swooped on some 17 non-governmental groups, part of a probe into what they say are illegal foreign funds for political activities.

Nazra was not raided but has faced a smear campaign.

"They said I was an American agent!" said Hassan, slumping her head on the desk in mock shame. "Our funding delays worsened after the revolution. It was hard anyway but it worsened."

The April 6 Youth Movement, one of the army's most prominent critics, has been labeled a foreign-funded agency doing the bidding of unnamed outsiders. Its members say they are regularly attacked by "concerned citizens" who think they are spies.

Many campaigners say the real revolution has not happened in the government but in the Egyptian people, who have found more courage to stand up for their rights.

"The real change is in the people who acted, people like me who had never been to a protest in my life before January 28 last year... Now there are thousands, hundreds of thousands who are willing to be part of this change," said Bakry.

Hassan agreed: "Uprisings are 18 days, protests are 18 days, but if you want use the word revolution in a difficult society like Egypt's... you are talking 10 years."

(Additional reporting by Tamim Elyan and Tom Perry; Editing by Tom Pfeiffer and Diana Abdallah)

Source: http://us.rd.yahoo.com/dailynews/rss/africa/*http%3A//news.yahoo.com/s/nm/20120123/wl_nm/us_egypt_revolution

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Google, MIT bestow App Inventor to the unwashed masses

Google must be feeling generous: it donated Sky Map to undeserving armchair astronomers and it's letting the great unwashed get at its App Inventor development platform. The software toolset was cooked up in partnership with MIT: a web-based interface that lets anyone build Android apps without getting elbows-deep in code. Those Massachusetts king-geeks won't be accepting submissions just yet, however: it's still got to work out how it's going to deploy the public server and foster a "robust and active open-source project" under its new name: the moderately unimaginative MIT App Inventor.

Google, MIT bestow App Inventor to the unwashed masses originally appeared on Engadget on Mon, 23 Jan 2012 21:52:00 EDT. Please see our terms for use of feeds.

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Monday, January 23, 2012

HRW calls on West to accept Islamist rise to power (AP)

CAIRO ? The United States and other Western governments must accept the new reality that Islamists have emerged to fill the power vacuum in the Arab world after a wave of popular uprisings, Human Rights Watch said in its annual report Sunday.

The New York-based group also urged Islamist parties, which have emerged as the biggest winners in recent elections in Tunisia and Egypt and are expected to fare well in Libya, to respect the rights of women and religious minorities, saying they cannot "pick and choose" when it comes to human rights.

Islamist parties are "genuinely popular" in the Arab world, said HRW's executive director, Kenneth Roth, warning that "ignoring that popularity would violate democratic principles."

"Being a political Islamic government should not be a reason to turn a government into a pariah," Roth told reporters in Cairo, where the group released its annual report.

The Arab Spring revolts began in Tunisia in late 2010 and quickly spread to Egypt, Libya, Yemen, Syria and Bahrain, deposing or challenging authoritarian rulers as citizens who long seemed incapable or unwilling to rise against decades of repression took to the streets in a stunning awakening.

Since the collapse of the regimes in Egypt and Tunisia a year ago, Islamist groups once largely confined to the political sidelines, such as the Muslim Brotherhood, have formed parties and contested parliamentary polls, winning the greatest share of seats.

Even the ultraconservative Salafis, who abstained from politics under Egypt's ousted President Hosni Mubarak, have fared well, winning more than 20 percent of the vote in the country's first post-uprising ballot.

Roth was cautious when asked about concerns about potential human rights violations under Islamist rule. He said that so far, Islamists have said "a lot of right things," but said the true test will be how they deal with the full sweep of human rights once in power.

"These are the big questions," he said.

The Muslim Brotherhood, for example, has been most interested in political freedoms, but Roth noted that "it is very difficult to secure political freedom if you are not respecting religious and women rights."

In some ways, the unexpected Arab uprisings have amounted to a slap to the United States and other Western governments, which had supported autocratic regimes that served as bulwarks against Islamists hostile to the West and appeared to offer stability in a volatile region.

"The West backed an array of autocrats as long as they, in turn, supported Western interests," Roth said. "The West is still adjusting to this historic transformation."

He added that the wave of uprisings "show that the forced silence of people living under autocrats should never have been mistaken for popular complacency."

Roth acknowledged Western governments were re-evaluating their policies as new governments emerge in the region.

Western nations have been accused of being selective in supporting the protesters, with NATO airstrikes proving key to the ouster of slain Libyan strongman Moammar Gadhafi. Meanwhile, the West has stood largely on the sidelines amid continued crackdowns in Bahrain, Yemen and Syria.

"The people driving the Arab Spring deserve strong international support to realize their rights and to build genuine democracies," Roth said in the group's annual report, which covers some 90 countries. He added that the Arab world is in a "transformative moment," and it will not be an easy one.

Human Rights Watch pointed to five main issues that dominated the relationship between Western governments and their Arab autocratic friends: the threat of political Islam, the fight against terrorism, support for Israel, protection of the oil flow and cooperation in stemming immigration.

Even after the leaders of Egypt, Libya and Tunisia were toppled, Western governments remained hesitant to lean too hard on other shaky authoritarian leaders, the group said. China and Russia acted "obstructionist," using their veto power at the U.N. security council to halt pressure on Syria to stop killings of protesters.

The popular uprisings also have alarmed other repressive regimes such as China, Zimbabwe, North Korea, Ethiopia, Vietnam, and Uzbekistan, where rulers were worried about facing similar fates.

"The worst response to the Arab Spring is the dictatorial world who are living in fear of the precedents set in this region," Roth said. "China greatly deepened its repression in an effort to avoid jasmine rallies."

Saudi Arabia also continues to discriminate against its citizens and workers, according to HRW, which said 9 million women, 8 million foreign workers and 2 million Shiite citizens are either suppressed or lacking rights in the country.

Outside the Arab world, the last year did not witness significant progress in countries with poor human rights records, including China and North Korea, according to the report.

Corruption, poverty and repression still prevail in Equatorial Guinea, the tiny, oil-rich nation off the western coast of Africa, which has been ruled by Africa's longest-serving ruler, Teodoro Obiang Nguema, the group said.

Eritrea continues to be governed by "one of the world's most repressive governments," and its citizens are subjected to torture, detentions and restrictions on freedom of speech, HRW said.

It also cited Colombia, saying armed conflict in the South American country has displaced millions while paramilitary groups with ties to the security apparatus are on the rise.

Cuba, HRW said, remains "the only country in Latin America that represses virtually all forms of political dissent."

The group also claimed that even member states of the European Union have violated human rights through restrictive asylum and migration policies.

Source: http://us.rd.yahoo.com/dailynews/rss/us/*http%3A//news.yahoo.com/s/ap/20120122/ap_on_re_mi_ea/human_rights_report

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Sunday, January 22, 2012

Obama: State of the Union an economic blueprint

President Barack Obama speaks at a campaign event, Thursday, Jan. 19, 2012, at the Apollo Theatre in the Harlem neighborhood of New York. (AP Photo/Haraz N. Ghanbari)

President Barack Obama speaks at a campaign event, Thursday, Jan. 19, 2012, at the Apollo Theatre in the Harlem neighborhood of New York. (AP Photo/Haraz N. Ghanbari)

(AP) ? President Barack Obama says his State of the Union address will be a blueprint for an economy that's "built to last" for the middle class.

He says he'll frame Tuesday's night national address to Congress around at least four themes. They are manufacturing, energy, education and what he calls "a return to American values."

The president briefly previewed elements of the speech in a video released by his re-election campaign Saturday to millions of Obama supporters.

Obama is seeking re-election in an atmosphere dominated by economic concerns, and his speech will amount to his vision for a second presidential term.

He says in the video that the nation must build an economy "that works for everyone, not just a wealthy few."

Central themes of the speech will be fairness, opportunity and rewards for hard work.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/f70471f764144b2fab526d39972d37b3/Article_2012-01-21-Obama-State%20of%20the%20Union/id-4c88d301270440d6bf5db692be9a9c8c

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3 die in house fire near Marist College

By NBC New York

An early-morning fire at a house near Marist College Saturday has left at three dead and four others with smoke inhalation, authorities said.

In a press conference held Saturday afternoon, Poughkeepsie Police confirmed that two female students from nearby Marist College and a male in his 20s died in the fire. Police said that the male victim was not a student.?

Four others escaped from the house with smoke inhalation, and were treated and released from the hospital.?

The fire began sometime after 1 a.m at 112 Fairview Avenue, officials said. The fire chief believes the fire may have started in the back of the house. ?

In a statement, Marist College said that school security and other officials are "working closely with the emergency responders to gather more information about the incident." ?

The house was privately owned and was not affiliated with the college.? ?

The Town of Poughkeepsie police are in charge at the scene, and continue their investigation. ?

An eyewitness told the Poughkeepsie Journal that she drove down Fairview Ave. at 1:20 a.m and saw the green house on fire. While standing on the street, she saw a female "fly through" a first floor window, breaking the glass. ?

"Apparently her boyfriend threw her out," she told the paper. The female and her boyfriend were both taken to the hospital and survived. ?

The identities of the victims have not been released at this time.

More content from msnbc.com and NBC News

Source: http://usnews.msnbc.msn.com/_news/2012/01/21/10207477-3-die-in-house-fire-near-marist-college

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Saturday, January 21, 2012

Mineral quashes deadly bacterial poisons

In animals, manganese shows promise fighting a hemorrhagic E. coli toxin

Web edition : 12:16 pm

A simple mineral supplement ? manganese ? holds promise as the first successful treatment for hemorrhage-inducing infections caused by some food- and waterborne germs. The mineral helps detoxify Shiga toxin, which is produced by a host of bacteria, including the type of E. coli that killed scores and sickened more than 3,700 people in Europe last year.

The new work, by researchers at Carnegie Mellon University in Pittsburgh, appears in the Jan. 20 Science.

Although the data are preliminary, ?it?s an exciting finding,? says microbiologist Vernon Tesh of the Texas A&M Health Science Center in Bryan, who did not participate in the new study. Manganese might soon offer a low-cost treatment that physicians could administer ?to every patient that comes into the clinic with a bloody stool,? he says.

?That would be a tremendous boon,? he adds, because although antibiotics can wipe out germs responsible for these infections, such drugs are strongly discouraged. Killing the bugs only expedites their release of Shiga toxin, increasing a patient?s risk of kidney failure, stroke and death.

The new finding ?is a classic example of serendipity in science,? says coauthor Adam Linstedt, a cell biologist at Carnegie Mellon. His team has been exploring the somewhat mysterious cellular role of a protein called GPP130. Then a colleague at the University of California, Santa Cruz reported the puzzling observation that giving cells manganese made their GPP130 disappear.

Normally, foreign materials entering a cell get tasted by an internal compartment called an endosome. Endosomes then shunt undesirable substances to another compartment, a lysosome, where they will be broken down and their raw materials discarded or recycled.

That should spell the end of Shiga toxin ? except it never reaches the lysosomes. Somewhere along the way, the poison hijacks protein-trafficking systems and forces a detour elsewhere in the cell. There the hijacker knocks out the cell?s life-sustaining machinery.

Linstedt and Somshuvra Mukhopadhyay, also of Carnegie Mellon, now show that it?s GPP130 that Shiga toxin hijacks. And manganese can defend GPP130 from that attack, allowing cells to shuttle the toxin directly to lysosomes, where it?s broken down into harmless components. In cells grown in a test tube and in mice, manganese pretreatment prevented death from the administration of pure Shiga toxin.

How clinically helpful that might be remains unclear. The toxin destroys the body?s smallest blood vessels, notes epidemiologist Dirk Werber of the Robert Koch Institute in Berlin. Vascular injury, which is the most dramatic consequence of infection with Shiga toxin-producing E. coli, ?is likely to be well under way by the time infected patients seek medical attention for diarrhea,? he says.

That?s true, Tesh acknowledges, although up to seven days can pass between the onset of bloody diarrhea and catastrophic vascular effects, as the toxin breaks out of the gut and begins circulating. So there would probably be a brief window when manganese treatment could save lives, he says.

The Carnegie Mellon researchers are now homing in on the minimum amount of manganese needed to protect animals, and hope to soon begin testing using Shiga-toxin-producing E. coli.


Found in: Food Science

Source: http://www.sciencenews.org/view/generic/id/337775/title/Mineral_quashes_deadly_bacterial_poisons

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6 Marines die in Afghanistan helicopter crash

By NBC News and news services

Updated at 3:33 a.m. ET: A helicopter crash in Helmand province in southern Afghanistan killed six U.S. Marines, the NATO?military command in Kabul told NBC News early Friday.

Officials said?there were no signs of enemy activity in the area at time of the crash.


The Marines have a substantial presence in Helmand province.

"We are still in the process of gathering more information on the incident," an official told Reuters.

It is the worst crash since last August?when 30 soldiers, including 22 elite Navy SEAL commandos, died when their helicopter came down in eastern Afghanistan.

The Helmand helicopter crash occurred on the same day seven civilians were killed outside a crowded gate at Kandahar Air Field, a sprawling base for U.S. and NATO operations, after a suicide attacker set off a vehicle laden with explosives. The Taliban claimed responsibility, saying?they were targeting a NATO convoy.

On Wednesday, 13 civilians, including three Afghan policemen, were killed when a suicide attacker blew himself up in a bazaar in? Helmand province. At least 22 others were wounded in the blast in Kajaki district.

????More from msnbc.com and NBC News:

NBC News, The Associated Press?and Reuters contributed to this report.

Source: http://worldnews.msnbc.msn.com/_news/2012/01/19/10194355-6-marines-die-in-afghanistan-helicopter-crash

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Friday, January 20, 2012

Split verdict in landmark Haiti prison riot trial (AP)

LES CAYES, Haiti ? A Haitian judge convicted seven police officers Thursday on various charges for their role in a prison riot in which at least 10 prisoners were shot to death in the chaotic aftermath of the January 2010 earthquake.

Judge Ezekiel Vaval said six other police officers were innocent as he concluded a three-month trial in the southwestern town of Les Cayes that was a closely watched test of the judicial system in the impoverished country.

The 13 police officers were accused of murder, attempted murder and other crimes after they allegedly opened fire on inmates during a prison riot in Les Cayes one week after the quake.

The sentences ranged from two years to 13 years of hard labor. The defendants faced up to life in prison.

"The decision of the judge is his expression of the truth," Vaval said in the packed courtroom. "There are other versions that exist but this is mine. And that is the law."

Lawyers for the officers had argued that the police officers were trying to break up a riot under difficult circumstances and it was unclear who actually shot the prisoners, saying some may have been killed by fellow inmates.

The trial itself was a rare occurrence in Haiti, a country where the judicial system barely functions and public officials are rarely held to account. The judge told The Associated Press before the verdict that he had received threatening phone calls and feared for his life.

Twenty-one other officers who fled will be tried in absentia.

Source: http://us.rd.yahoo.com/dailynews/rss/latam/*http%3A//news.yahoo.com/s/ap/20120119/ap_on_re_la_am_ca/cb_haiti_prison_trial

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